Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642877 | 0.81 | MMP1 (0.55) | MMP1MMP2CRBNALDH1A1CYP3A4 | |
| SCHEMBL10187474 | 0.81 | MMP2 (0.51) | MMP1MMP2ALDH1A1KMT2AGAA | |
| SCHEMBL11453294 | 0.78 | MAPT (0.58) | MMP1MMP2CRBNNPC1ALDH1A1 | |
| SCHEMBL6624682 | 0.77 | MMP1 (0.48) | MMP1MMP2ALDH1A1MAPTGAA | |
| SCHEMBL9423564 | 0.75 | PRMT5 (0.54) | MMP1MMP2ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL9423475 | 0.75 | PRMT5 (0.54) | MMP1MMP2ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL7468390 | 0.75 | PRMT5 (0.54) | MMP1MMP2ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL4292169 | 0.75 | MMP2 (0.67) | MMP1MMP2ALDH1A1KMT2AHTT | |
| SCHEMBL4819794 | 0.74 | CRBN (0.51) | CRBNNPC1ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL12717348 | 0.74 | MMP2 (0.69) | MMP1MMP2ALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4200654-A | 3-SUBSTITUTED AMINO-2-HYDROXY-PROPYL ETHERS, SULFIDES, OR SULFONES | ABBOTT LABORATORIES (US) | 1980-04-29 | — | — | US | disclosed |