Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033497 | 0.78 | ALDH1A1 (0.59) | MAPTALDH1A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL20336352 | 0.78 | MAPT (0.60) | SLC6A9MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL29937559 | 0.78 | MAPT (0.68) | SLC6A9MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL3485340 | 0.78 | MAPT (0.68) | SLC6A9MAPTALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11492243 | 0.78 | KDM4E (0.59) | SLC6A9MAPTALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL5235027 | 0.76 | ALDH1A1 (0.59) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL11883541 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL23850714 | 0.74 | MAPT (0.62) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL31588237 | 0.74 | MAPT (0.62) | MAPTALDH1A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL2533103 | 0.72 | SMN1; SMN2 (0.66) | SLC6A9MAPTALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4209528-A | Antisecretory oxamic acid esters | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-06-24 | — | — | US | disclosed |
| US-4137325-A | Antisecretory oxamic acid esters | AMERICAN HOME PRODUCTS CORPORATION (US) | 1979-01-30 | — | — | US | disclosed |