Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11124749 | 0.88 | TDP1 (0.49) | KMT2ATDP1MEN1MAPTPOLB | |
| SCHEMBL11484267 | 0.81 | TDP1 (0.45) | KMT2ATDP1MEN1MAPTPOLB | |
| SCHEMBL18815092 | 0.80 | TSHR (0.54) | KMT2ATDP1MEN1MAPTPOLB | |
| SCHEMBL10652156 | 0.77 | MAPT (0.55) | KMT2ATDP1MEN1MAPTPOLB | |
| SCHEMBL11633022 | 0.77 | TSHR (0.51) | KMT2ATDP1MEN1MAPTPOLB | |
| SCHEMBL8515801 | 0.77 | MAPT (0.57) | KMT2ATDP1MEN1MAPTPOLB | |
| SCHEMBL10827907 | 0.77 | ALDH1A1 (0.36) | KMT2ATDP1MEN1MAPTALDH1A1 | |
| SCHEMBL28506022 | 0.77 | TDP1 (0.62) | KMT2ATDP1MEN1MAPTPOLB | |
| SCHEMBL11526384 | 0.76 | TSHR (0.50) | KMT2ATDP1MEN1MAPTPOLB | |
| SCHEMBL11326081 | 0.76 | TSHR (0.50) | KMT2ATDP1MEN1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599428-A | SALT FORMATION, THIOETHERIFICATION | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1986-07-08 | — | — | US | disclosed |
| US-4473697-A | WITH GASEOUS CHLORINE AND A RHODANIDE | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA R.T. (HU) | 1984-09-25 | — | — | US | disclosed |
| EP-0027646-B1 | PROCESS FOR THE PREPARATION OF BENZIMIDAZOLE DERIVATIVES | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1984-03-07 | — | — | EP | disclosed |
| EP-0027646-A1 | Process for the preparation of benzimidazole derivatives | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1981-04-29 | — | — | EP | disclosed |
| US-4072696-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1978-02-07 | — | — | US | disclosed |