Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | GRK5 | P34947 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498864 | 0.68 | NOS2 (0.41) | ADRA2AADRA2BNOS2USP2PLK4 | |
| SCHEMBL2874924 | 0.62 | CES1 (0.43) | NOS2 | |
| SCHEMBL15219995 | 0.62 | CES1 (0.50) | ADRA2AADRA2BNOS2USP2PLK4 | |
| SCHEMBL15280125 | 0.60 | HSP90AA1 (0.33) | POLBGAA | |
| SCHEMBL911054 | 0.59 | — | — | |
| SCHEMBL19752571 | 0.59 | GPR3 (0.40) | DRD2DRD1DRD3 | |
| SCHEMBL15492687 | 0.58 | HRH1 (0.35) | DRD2DRD1HRH1 | |
| SCHEMBL6331465 | 0.58 | USP2 (0.47) | ADRA2AADRA2BNOS2USP2PLK4 | |
| SCHEMBL4584548 | 0.58 | PLK4 (0.47) | ADRA2AADRA2BNOS2USP2PLK4 | |
| SCHEMBL19273850 | 0.57 | FFAR4 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4191830-A | HERBICIDES AND ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1980-03-04 | — | — | US | disclosed |
| US-4156670-A | UREAS AND THIOUREAS, HERBICIDES, ANIMAL GROWTH REGULATORS | AMERICAN CYANAMID COMPANY (US) | 1979-05-29 | — | — | US | disclosed |
| US-4036979-A | ANIMAL GROWTH RATE ACCELERATOR | AMERICAN CYANAMID COMPANY (US) | 1977-07-19 | — | — | US | disclosed |