Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14372259 | 0.72 | TSHR (0.48) | CHRM2CHRM1CHRM3TSHRKDM4E | |
| SCHEMBL11493008 | 0.71 | SIGMAR1 (0.43) | — | |
| SCHEMBL11483424 | 0.69 | ATM (0.49) | TSHRKDM4ELMNANPSR1ALDH1A1 | |
| SCHEMBL14964726 | 0.67 | PDK1 (0.32) | — | |
| SCHEMBL11492546 | 0.65 | TSHR (0.48) | CHRM2CHRM1CHRM3TSHRKDM4E | |
| SCHEMBL10512865 | 0.64 | TSHR (0.55) | CHRM2CHRM1TSHRLMNATP53 | |
| SCHEMBL3879203 | 0.63 | TSHR (0.53) | CHRM2CHRM1CHRM3TSHRNPSR1 | |
| SCHEMBL4636666 | 0.63 | ACP3 (0.52) | CHRM2CHRM1CHRM3TSHRLMNA | |
| SCHEMBL11105741 | 0.62 | ACP3 (0.50) | CHRM2CHRM1CHRM3TSHRNPSR1 | |
| SCHEMBL7171729 | 0.62 | ACP3 (0.50) | CHRM2CHRM1CHRM3TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188485-A | NEUROLEPTIC, CORRESPONDING XANTHENES AND THIOANTHENES | G. D. SEARLE & CO. (US) | 1980-02-12 | — | — | US | disclosed |