Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485032 | 1.00 | ALDH1A1 (0.39) | ALDH1A1POLBGLAMAPTHPGD | |
| SCHEMBL28147365 | 0.78 | ALDH1A1 (0.48) | ALDH1A1POLBGLAMAPTHPGD | |
| SCHEMBL27892779 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTHPGDGAAKMT2A | |
| SCHEMBL18947245 | 0.73 | MEN1 (0.39) | ALDH1A1POLBGLAMAPTHPGD | |
| SCHEMBL5773977 | 0.72 | NPSR1 (0.41) | ALDH1A1POLBGLAMAPTHPGD | |
| SCHEMBL29959966 | 0.72 | MEN1 (0.48) | ALDH1A1POLBGLAMAPTHPGD | |
| SCHEMBL66606 | 0.72 | MEN1 (0.48) | ALDH1A1POLBGLAMAPTHPGD | |
| SCHEMBL5526432 | 0.72 | MEN1 (0.48) | ALDH1A1POLBGLAMAPTHPGD | |
| SCHEMBL1332400 | 0.72 | MEN1 (0.48) | ALDH1A1POLBGLAMAPTHPGD | |
| Dimethylformamide SCHEMBL7593237 | 0.72 | POLB (0.39) | ALDH1A1POLBGLAMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239901-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-12-16 | — | — | US | disclosed |