Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809030 | 0.80 | MAPT (0.45) | ALDH1A1TSHRRAB9AHPGDNPC1 | |
| SCHEMBL5779893 | 0.78 | NPSR1 (0.44) | NPSR1HTTKMT2AALDH1A1GLA | |
| SCHEMBL10341221 | 0.78 | HSD17B2 (0.51) | KMT2AMEN1ALDH1A1HPGDKDM4E | |
| SCHEMBL5089790 | 0.77 | MEN1 (0.58) | NPSR1KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL9371442 | 0.76 | ATM (0.35) | KMT2AMEN1ALDH1A1RAB9ANPC1 | |
| SCHEMBL18947245 | 0.76 | MEN1 (0.39) | NPSR1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28906894 | 0.75 | LMNA (0.48) | KMT2AALDH1A1NPC1POLBGAA | |
| SCHEMBL10375754 | 0.75 | ALDH1A1 (0.48) | NPSR1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL5765975 | 0.75 | NPSR1 (0.38) | NPSR1HTTKMT2AMEN1ALDH1A1 | |
| SCHEMBL28147365 | 0.73 | ALDH1A1 (0.48) | NPSR1HTTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513833-B1 | NOVEL 3-(4-OXO-4H-CHROMEN-2-YL)-(1H)-QUINOLINE-4-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2006-04-19 | — | — | EP | disclosed |
| EP-1513833-A1 | NOVEL 3-(4-OXO-4H-CHROMEN-2-YL)-(1H)-QUINOLINE-4-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2005-03-16 | — | — | EP | disclosed |
| WO-2004000834-A1 | NOVEL 3-(4-OXO-4H-CHROMEN-2-YL)-(1H)-QUINOLINE-4-ONE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2003-12-31 | — | — | WO | disclosed |