Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29897004 | 0.82 | MAOA (0.46) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1355341 | 0.82 | MAOA (0.46) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1355343 | 0.82 | MAOA (0.46) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL710570 | 0.74 | NPC1 (0.49) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL11492822 | 0.72 | KMT2A (0.46) | MAOAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL7093346 | 0.72 | MAOA (0.44) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL11492818 | 0.72 | KMT2A (0.46) | MAOAKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL9095846 | 0.71 | — | — | |
| SCHEMBL6375021 | 0.68 | NOS3 (0.42) | MAOAMAOBADRA2AADRA2BADRA2C | |
| SCHEMBL1853723 | 0.67 | MAOA (0.50) | MAOAMAOBADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239901-A | ANALGESICS, ANTIPYRETICS, ANTIINFLAMMATORY AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1980-12-16 | — | — | US | disclosed |