⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492319 | 0.85 | ADRB2 (0.34) | — | |
| SCHEMBL11487870 | 0.85 | — | — | |
| SCHEMBL11483684 | 0.84 | CNR1 (0.34) | — | |
| SCHEMBL11485020 | 0.84 | CNR1 (0.34) | — | |
| SCHEMBL11483688 | 0.84 | CNR1 (0.34) | — | |
| SCHEMBL11483647 | 0.82 | CNR1 (0.32) | — | |
| SCHEMBL11493781 | 0.80 | OPRM1 (0.31) | — | |
| SCHEMBL11738988 | 0.79 | CNR1 (0.42) | — | |
| SCHEMBL11247589 | 0.79 | TRPV1 (0.32) | — | |
| SCHEMBL11492009 | 0.78 | CNR1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206225-A | ANALGESICS | PFIZER INC. (US) | 1980-06-03 | — | — | US | disclosed |
| EP-0009386-A1 | 2,10-Disubstituted dibenzo(b,d)pyrans and benzo(c)quinolines and pharmaceutical compositions thereof | PFIZER INC. (US) | 1980-04-02 | — | — | EP | disclosed |