Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485879 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BNQO2MEN1MAPT | |
| SCHEMBL11496113 | 0.85 | MTNR1A (0.47) | MTNR1AMTNR1BMEN1MAPTKMT2A | |
| SCHEMBL11496110 | 0.85 | MTNR1A (0.47) | MTNR1AMTNR1BMEN1MAPTKMT2A | |
| SCHEMBL11490951 | 0.84 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTKMT2AALDH1A1 | |
| SCHEMBL11490955 | 0.84 | MTNR1A (0.49) | MTNR1AMTNR1BMAPTKMT2AALDH1A1 | |
| SCHEMBL11540592 | 0.82 | ALOX15 (0.32) | NQO2HSD17B1 | |
| SCHEMBL11540590 | 0.82 | ALOX15 (0.32) | NQO2HSD17B1 | |
| SCHEMBL11489699 | 0.80 | ALOX15 (0.31) | — | |
| SCHEMBL11496269 | 0.79 | ALOX15 (0.41) | MTNR1AMTNR1BMEN1MAPTKMT2A | |
| SCHEMBL11496267 | 0.79 | ALOX15 (0.41) | MTNR1AMTNR1BMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |