Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486129 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2USP2ALOX15TSHRALDH1A1 | |
| SCHEMBL11469183 | 0.87 | HRH3 (0.48) | SMN1; SMN2USP2ALOX15TSHRHRH3 | |
| SCHEMBL11488887 | 0.83 | MAOB (0.41) | SMN1; SMN2USP2ALOX15TSHRALDH1A1 | |
| SCHEMBL11489440 | 0.83 | KDM4E (0.50) | ALDH1A1KMT2AMEN1KDM4EHPGD | |
| SCHEMBL11494289 | 0.82 | TSHR (0.43) | SMN1; SMN2USP2ALOX15TSHRALDH1A1 | |
| SCHEMBL11494574 | 0.81 | ALDH1A1 (0.47) | SMN1; SMN2USP2ALOX15TSHRALDH1A1 | |
| SCHEMBL3574805 | 0.79 | TSHR (0.71) | SMN1; SMN2USP2ALOX15TSHRALDH1A1 | |
| SCHEMBL3574801 | 0.79 | TSHR (0.71) | SMN1; SMN2USP2ALOX15TSHRALDH1A1 | |
| SCHEMBL11493711 | 0.78 | USP2 (0.39) | SMN1; SMN2USP2ALOX15TSHRALDH1A1 | |
| SCHEMBL11487234 | 0.78 | KDM4E (0.41) | SMN1; SMN2USP2ALOX15TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4241058-A | INSECTICIDES, MITICIDES, SYSTEMIC | HOFFMANN-LA ROCHE INC. (US) | 1980-12-23 | — | — | US | disclosed |