Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486767 | 1.00 | ALDH1A1 (0.35) | ALDH1A1HSD17B10KDM4ELMNACYP3A4 | |
| SCHEMBL11483160 | 1.00 | ALDH1A1 (0.35) | ALDH1A1HSD17B10KDM4ELMNACYP3A4 | |
| SCHEMBL11491393 | 0.98 | ALDH1A1 (0.33) | ALDH1A1HSD17B10KDM4ELMNACYP3A4 | |
| SCHEMBL11484909 | 0.82 | CHRM2 (0.39) | ALDH1A1HSD17B10KDM4ELMNACYP3A4 | |
| SCHEMBL11486759 | 0.82 | CHRM2 (0.39) | ALDH1A1HSD17B10KDM4ELMNACYP3A4 | |
| SCHEMBL11482881 | 0.82 | KDM4E (0.37) | ALDH1A1HSD17B10KDM4ELMNADRD2 | |
| SCHEMBL11484945 | 0.82 | KDM4E (0.37) | ALDH1A1HSD17B10KDM4ELMNADRD2 | |
| SCHEMBL11486725 | 0.82 | DRD2 (0.41) | ALDH1A1HSD17B10KDM4ELMNATP53 | |
| SCHEMBL11495369 | 0.82 | KDM4E (0.37) | ALDH1A1HSD17B10KDM4ELMNADRD2 | |
| SCHEMBL11484222 | 0.82 | KDM4E (0.37) | ALDH1A1HSD17B10KDM4ELMNADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4185152-A | ANTIRADIATION AGENTS | WARNER-LAMBERT COMPANY (US) | 1980-01-22 | — | — | US | disclosed |