Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | PRCP | P42785 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 3/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TLR2 | O60603 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CPN1 | P15169 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495504 | 0.84 | DPP7 (0.32) | DPP7PRCPDPP4DPP8 | |
| SCHEMBL7127502 | 0.83 | PRCP (0.37) | CPB2DPP7PRCPDPP4SLC6A2 | |
| SCHEMBL11376986 | 0.83 | PRCP (0.37) | CPB2DPP7PRCPDPP4SLC6A2 | |
| SCHEMBL11433291 | 0.83 | CPN1 (0.38) | CPB2DPP7PRCPDPP4DPP8 | |
| SCHEMBL11335822 | 0.81 | CPB2 (0.35) | CPB2DPP7PRCPCPN1 | |
| SCHEMBL11618241 | 0.81 | PRCP (0.38) | DPP7PRCPDPP4DPP8SLC6A2 | |
| SCHEMBL11432121 | 0.80 | DPP7 (0.32) | CPB2DPP7PRCPCPN1 | |
| SCHEMBL11434881 | 0.79 | CPN1 (0.35) | CPB2DPP7PRCPDPP4DPP8 | |
| SCHEMBL11324776 | 0.79 | CPB2 (0.42) | CPB2DPP7PRCPDPP4DPP8 | |
| SCHEMBL11485912 | 0.79 | PRCP (0.34) | CPB2DPP7PRCPKMT2ATLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4198517-A | Histidine derivatives | E. R. SQUIBB & SONS, INC. (US) | 1980-04-15 | — | — | US | disclosed |
| US-4154736-A | Indolylalkylene amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4128721-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1978-12-05 | — | — | US | disclosed |
| US-4127729-A | Amino acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4091024-A | Pyrrolidine and piperidine-2-carboxylic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1978-05-23 | — | — | US | disclosed |