Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CPN1 | P15169 | 3/20 | 0.35 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | SCN4A | P35499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376986 | 1.00 | PRCP (0.37) | PRCPDPP7CPN1CPB2TLR2 | |
| SCHEMBL11433291 | 0.91 | CPN1 (0.38) | PRCPDPP7CPN1CPB2TLR2 | |
| SCHEMBL4667895 | 0.91 | PRCP (0.40) | PRCPDPP7TLR2CYP1A2CYP3A4 | |
| SCHEMBL11434881 | 0.87 | CPN1 (0.35) | PRCPDPP7CPN1CPB2TLR2 | |
| SCHEMBL11430661 | 0.86 | MEN1 (0.34) | PRCPDPP7CPN1CPB2TLR2 | |
| SCHEMBL11326269 | 0.86 | CPN1 (0.35) | PRCPDPP7CPN1CPB2TLR2 | |
| SCHEMBL11487748 | 0.84 | CPN1 (0.37) | PRCPDPP7CPN1CPB2CYP1A2 | |
| SCHEMBL11485912 | 0.84 | PRCP (0.34) | PRCPDPP7CPN1CPB2TLR2 | |
| SCHEMBL11486295 | 0.83 | CPB2 (0.34) | PRCPDPP7CPN1CPB2TLR2 | |
| SCHEMBL11484027 | 0.83 | NOS2 (0.36) | PRCPCPN1CPB2NOS2NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1294728-A1 | HMG-CoA REDUCTASE INHIBITORS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-03-26 | — | — | EP | disclosed |
| WO-2001096347-A1 | HMG-CoA REDUCTASE INHIBITORS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-20 | — | — | WO | disclosed |