Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.49 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11475639 | 0.84 | HPGDS (0.44) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL11490893 | 0.78 | BCHE (0.51) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL24471264 | 0.78 | HIF1A (0.55) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL3138286 | 0.78 | TTR (0.53) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL13996817 | 0.74 | KDM4E (0.49) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL11107537 | 0.73 | KDM4E (0.80) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL10860642 | 0.73 | FABP4 (0.64) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL2398642 | 0.73 | KDM4E (0.67) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL16144996 | 0.73 | KDM4E (0.59) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL8907760 | 0.73 | KDM4E (0.67) | KDM4EMAPTHIF1ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4195984-A | Herbicides derived from dihalo isonicotinoyl derivatives of amino acids | ABBOTT LABORATORIES (US) | 1980-04-01 | — | — | US | disclosed |