Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946811 | 0.78 | GPR84 (0.62) | GPR84MAPTGAAALDH1A1 | |
| Ethyne SCHEMBL28448752 | 0.74 | GPR84 (0.58) | GPR84 | |
| SCHEMBL13068587 | 0.71 | MAPT (0.48) | MAPTGAALRRK2PDGFRAFER | |
| SCHEMBL11619520 | 0.71 | GAA (0.48) | MAPTGAALRRK2PDGFRAFER | |
| SCHEMBL11621872 | 0.71 | GAA (0.48) | MAPTGAALRRK2PDGFRAFER | |
| SCHEMBL11489366 | 0.71 | MAPT (0.48) | MAPTGAALRRK2PDGFRAFER | |
| Bromide SCHEMBL11620749 | 0.69 | GAA (0.46) | MAPTGAALRRK2PDGFRAFER | |
| Ammonia Solution, Strong SCHEMBL3949938 | 0.69 | GPR84 (0.53) | GPR84 | |
| SCHEMBL29624824 | 0.67 | GPR84 (0.50) | GPR84MAPTMAOARAB9AMAPK1 | |
| SCHEMBL2781483 | 0.67 | GPR84 (0.50) | GPR84MAPTMAOARAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235895-A | FOR TREATING EPILEPSY | CIBA-GEIGY CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| EP-0011603-A1 | 10-Nitrilo-5H-dibenz(b,f)azepine-5-carboxamide, process for its preparation and pharmaceutical compositions containing it | CIBA-GEIGY AG (CH) | 1980-05-28 | — | — | EP | disclosed |