Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27758988 | 0.74 | GAA (0.58) | MAPTGAARAB9ANPC1PTGS2 | |
| SCHEMBL30040907 | 0.72 | GAA (0.59) | MAPTCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL11208844 | 0.72 | GAA (0.59) | MAPTCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL7752909 | 0.72 | MAPT (0.68) | MAPTCYP1A2CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11142311 | 0.72 | PTGS2 (0.75) | MAPTGAARAB9ANPC1PTGS2 | |
| SCHEMBL29050275 | 0.71 | PRKCI (0.43) | MAPTCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL29106631 | 0.70 | NPC1 (0.49) | MAPTCYP1A2CYP2C9CYP2C19RAB9A | |
| Urea SCHEMBL11319525 | 0.70 | PRKCI (0.42) | MAPTCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL1548172 | 0.70 | MAPT (1.00) | MAPTCYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL27518374 | 0.70 | MAPT (0.62) | MAPTCYP1A2CYP2C9CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204056-A | Process and intermediates for preparing fiber-reactive phthalocyanine dyes | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-05-20 | — | — | US | disclosed |
| US-4191686-A | FROM SULFONYL HALIDE SUBSTITUTED PARENT BY AMIDATION WITH AROMATIC DIAMINE, DIAZOTIZING, COUPLING TO KETO SUCCINIC ESTER, CYCLIZING, COUPLING TO REACTIVE MOIETY | CASSELLA AKTIENGESELLSCHAFT (DE) | 1980-03-04 | — | — | US | disclosed |