Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.50 |
| ▸ | PDE4A | P27815 | 3/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.44 |
| ▸ | QDPR | P09417 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11719342 | 0.86 | MEN1 (0.45) | MEN1KMT2APDE4BPDE4APDE4C | |
| SCHEMBL11477940 | 0.85 | FFAR4 (0.48) | MEN1KMT2APDE4BPDE4APDE4C | |
| SCHEMBL11389386 | 0.81 | ACMSD (0.58) | KMT2APTGDR2ACMSDQDPRKMO | |
| SCHEMBL20155928 | 0.79 | PDE4A (0.47) | KMT2APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL11724509 | 0.79 | ACMSD (0.57) | KMT2AACMSDQDPRKMO | |
| SCHEMBL28896136 | 0.78 | ACMSD (0.59) | KMT2APDE4BPDE4APDE4CPDE4D | |
| SCHEMBL10246888 | 0.78 | HTR2A (0.50) | PDE4BPDE4APDE4CPDE4DQDPR | |
| SCHEMBL27362435 | 0.78 | ACMSD (0.44) | PDE4BPDE4APDE4CPDE4DHSD17B10 | |
| SCHEMBL11480718 | 0.77 | PDE4B (0.47) | MEN1KMT2APDE4BPDE4APDE4C | |
| SCHEMBL2969812 | 0.77 | ACMSD (0.58) | PDE4BPDE4APDE4CPDE4DACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1898222-A | Substituted aryl cycloalkanol derivatives and methods of their use | WYETH CORP (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1897950-A | Fused aryl and heteroaryl derivatives and methods of use thereof | WYETH CORP (US) | 2007-01-17 | — | — | CN | disclosed |
| US-4232039-A | ANTIARTHRITIC, ANTIINFLAMMATORY, AND ANTIEDEMIC AGENTS | SANDOZ LTD. (CH) | 1980-11-04 | — | — | US | disclosed |
| US-4013690-A | ORGANIC COMPOUNDS | SANDOZ LTD. (CH) | 1977-03-22 | — | — | US | disclosed |