Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.53 |
| ▸ | PDE4A | P27815 | 3/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | QDPR | P09417 | 2/20 | 0.47 |
| ▸ | CFB | P00751 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2969812 | 0.98 | ACMSD (0.58) | ACMSDPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL25861565 | 0.92 | ALDH1A1 (0.56) | ACMSDPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL11724514 | 0.88 | PDE4B (0.50) | ACMSDPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL27592891 | 0.88 | ACMSD (0.62) | ACMSDPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL29196219 | 0.85 | PDE4B (0.50) | ACMSDPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL11480718 | 0.84 | PDE4B (0.47) | ACMSDPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL10435909 | 0.83 | PDE4A (0.60) | ACMSDPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL10638574 | 0.82 | PDE4B (0.48) | ACMSDPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL28645076 | 0.81 | ACMSD (0.61) | ACMSDPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL23374556 | 0.80 | ACMSD (0.75) | ACMSDALDH1A1KMOKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111995567-B | Formamide pyridone iron chelator derivative with potential multi-target anti-AD activity and preparation method and application thereof | 浙江工业大学 | 2022-11-25 | — | — | CN | disclosed |