Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.33 |
| ▸ | DRD4 | P21917 | 4/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11609680 | 0.85 | L3MBTL1 (0.53) | L3MBTL1SMN1; SMN2MAPK1DRD2DRD4 | |
| SCHEMBL9444177 | 0.78 | L3MBTL1 (0.57) | L3MBTL1SMN1; SMN2MAPK1DRD2ACHE | |
| Hydrochloric Acid SCHEMBL9444156 | 0.77 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2MAPK1DRD2ACHE | |
| SCHEMBL9485683 | 0.74 | L3MBTL1 (0.68) | L3MBTL1SMN1; SMN2MAPK1DRD2DRD4 | |
| SCHEMBL9485715 | 0.73 | L3MBTL1 (0.51) | L3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL11608316 | 0.72 | L3MBTL1 (0.43) | L3MBTL1SMN1; SMN2MAPK1DRD2DRD4 | |
| SCHEMBL11675386 | 0.71 | L3MBTL1 (0.58) | L3MBTL1SMN1; SMN2MAPK1CHRM2CHRM4 | |
| SCHEMBL9444141 | 0.71 | L3MBTL1 (0.58) | L3MBTL1SMN1; SMN2MAPK1CHRM2CHRM4 | |
| SCHEMBL9486504 | 0.71 | L3MBTL1 (0.49) | L3MBTL1SMN1; SMN2MAPK1DRD2ACHE | |
| SCHEMBL11615421 | 0.71 | L3MBTL1 (0.42) | L3MBTL1SMN1; SMN2MAPK1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4223035-A | ANTIDEPRESSANT, ANTICHOLINERGIC, HORMONE INHIBITOR | SANDOZ LTD. (CH) | 1980-09-16 | — | — | US | disclosed |