Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD5 | P21918 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13921299 | 0.86 | MAPK1 (0.82) | L3MBTL1SMN1; SMN2MAPK1DRD2DRD1 | |
| SCHEMBL11675386 | 0.81 | L3MBTL1 (0.58) | L3MBTL1SMN1; SMN2MAPK1CHRM2CHRM1 | |
| SCHEMBL11484395 | 0.80 | L3MBTL1 (0.63) | L3MBTL1SMN1; SMN2MAPK1DRD2DRD1 | |
| SCHEMBL11484415 | 0.77 | L3MBTL1 (0.59) | L3MBTL1SMN1; SMN2MAPK1 | |
| SCHEMBL9444141 | 0.76 | L3MBTL1 (0.58) | L3MBTL1SMN1; SMN2MAPK1CHRM2CHRM1 | |
| SCHEMBL9631976 | 0.75 | MAPK1 (0.73) | L3MBTL1SMN1; SMN2MAPK1CHRM2CHRM1 | |
| SCHEMBL9444177 | 0.75 | L3MBTL1 (0.57) | L3MBTL1SMN1; SMN2MAPK1DRD2DRD1 | |
| SCHEMBL7295187 | 0.75 | L3MBTL1 (0.70) | L3MBTL1SMN1; SMN2MAPK1DRD2DRD1 | |
| Hydrochloric Acid SCHEMBL9444156 | 0.74 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2MAPK1DRD2DRD1 | |
| SCHEMBL11487481 | 0.74 | L3MBTL1 (0.56) | L3MBTL1SMN1; SMN2MAPK1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5260319-A | Analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0435223-A2 | Thienobenzoxepin- and naphthothiophene-derivatives, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1991-07-03 | — | — | EP | disclosed |
| US-5006536-A | Thienobenzoxepins and analgesic compositions thereof | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1991-04-09 | — | — | US | disclosed |