Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.46 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11496019 | 1.00 | SLC6A4 (0.53) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11492535 | 0.99 | SLC6A4 (0.54) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11489416 | 0.92 | CHRM2 (0.49) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11489140 | 0.89 | SLC6A4 (0.56) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL11492985 | 0.88 | LTA4H (0.55) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11488504 | 0.88 | LTA4H (0.55) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11492669 | 0.87 | SLC6A4 (0.55) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11487551 | 0.87 | SLC6A4 (0.55) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2CCR2 | |
| SCHEMBL11487165 | 0.87 | SLC6A4 (0.52) | SLC6A4SLC6A3ALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL11487380 | 0.87 | CYP2D6 (0.59) | SLC6A4SLC6A3LMNACHRM2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |