Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11488209 | 1.00 | LSS (0.40) | LSSALDH1A1KDM4EMAPTAGTR1 | |
| SCHEMBL11493588 | 0.86 | SRD5A2 (0.39) | LSSALDH1A1MAPTMEN1MAPK1 | |
| SCHEMBL11495739 | 0.85 | MAPT (0.54) | ALDH1A1KDM4EMAPTAGTR1USP2 | |
| SCHEMBL11489797 | 0.84 | POLB (0.31) | ALDH1A1KDM4EMAPTAGTR1POLB | |
| SCHEMBL11489798 | 0.84 | POLB (0.31) | ALDH1A1KDM4EMAPTAGTR1POLB | |
| SCHEMBL11489667 | 0.83 | BCL2L1 (0.39) | ALDH1A1KDM4EMAPTAGTR1HRH3 | |
| SCHEMBL11489668 | 0.83 | BCL2L1 (0.39) | ALDH1A1KDM4EMAPTAGTR1HRH3 | |
| SCHEMBL11486848 | 0.83 | PTGS1 (0.39) | ALDH1A1KDM4EMAPTAGTR1HRH3 | |
| SCHEMBL11486851 | 0.83 | PTGS1 (0.39) | ALDH1A1KDM4EMAPTAGTR1HRH3 | |
| SCHEMBL11492883 | 0.80 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTAGTR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |