Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 6/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10836940 | 0.86 | ATM (0.53) | ADRB3ADRB2ADRB1ATMCYP1A2 | |
| SCHEMBL20436123 | 0.83 | ADRB3 (0.54) | ADRB3ADRB2ADRB1ATMCYP1A2 | |
| SCHEMBL11009261 | 0.82 | PLA2G4B (0.54) | ADRB3ADRB2ADRB1ATMCYP1A2 | |
| SCHEMBL18506359 | 0.82 | ADRB3 (0.60) | ADRB3ADRB2ADRB1ATMCYP1A2 | |
| SCHEMBL11488238 | 0.81 | ADRB3 (0.51) | ADRB3ADRB2ADRB1ATMCYP1A2 | |
| SCHEMBL10838546 | 0.78 | ADRB3 (0.66) | ADRB3ADRB2ADRB1MEN1KMT2A | |
| SCHEMBL20436115 | 0.78 | ADRB3 (0.54) | ADRB3ADRB2ADRB1MEN1KMT2A | |
| SCHEMBL11499941 | 0.77 | ADRB3 (0.53) | ADRB3ADRB2ADRB1ATMCYP1A2 | |
| SCHEMBL17038023 | 0.76 | ADRB3 (0.71) | ADRB3ADRB2ADRB1MEN1OPRM1 | |
| SCHEMBL17038022 | 0.76 | ADRB3 (0.71) | ADRB3ADRB2ADRB1MEN1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216314-A | CARDIOSELECTIVE B-ADRENOLYTIC AGENTS, ANTIARRHYTHMIC AGENTS AND HYPOTENSIVE AGENTS | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DE) | 1980-08-05 | — | — | US | disclosed |