Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.35 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.34 |
| ▸ | PPOX | P50336 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ESRRA | P11474 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1148994 | 0.86 | DHODH (0.35) | FFAR1MRGPRX4PDE2A | |
| SCHEMBL1148924 | 0.84 | FFAR1 (0.37) | FFAR1MRGPRX4STK39MEN1TTR | |
| SCHEMBL1149037 | 0.79 | FFAR1 (0.37) | FFAR1MRGPRX4MEN1TTRPPOX | |
| SCHEMBL1149034 | 0.72 | RAF1 (0.35) | FFAR1MRGPRX4 | |
| SCHEMBL10707742 | 0.71 | FFAR1 (0.54) | FFAR1MRGPRX4MEN1TTRPPOX | |
| SCHEMBL2820687 | 0.70 | AR (0.33) | — | |
| SCHEMBL1149078 | 0.69 | CCNC (0.37) | STK39MEN1KMT2AKDM4E | |
| SCHEMBL1148847 | 0.69 | RAF1 (0.39) | MEN1KMT2AKDM4E | |
| SCHEMBL7803868 | 0.68 | AR (0.46) | FFAR1MRGPRX4MEN1TTRPPOX | |
| SCHEMBL7803948 | 0.68 | TTR (0.49) | FFAR1MRGPRX4MEN1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1780202-B1 | QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |
| US-7880006-B2 | 4-Acetoxy-5-chloro-6-(4-chlorophenoxy)-2,3-dimethyl-quinoline, used as agricultural and horticultural insecticides | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-02-01 | — | — | US | disclosed |
| US-20070203181-A1 | Quinoline Derivatives And Insecticide Comprising Thereof As Active Ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-08-30 | — | — | US | disclosed |
| EP-1780202-A1 | QUINOLINE DERIVATIVE AND INSECTICIDE CONTAINING SAME AS ACTIVE CONSTITUENT | MEIJI SEIKA KAISHA LTD. (JP) | 2007-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070203181-A1 | Quinoline Derivatives And Insecticide Comprising Thereof As Active Ingredient | DDT, ACHE, NQO1 | FFAR1 2742/4885MRGPRX4 3431/4885STK39 915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.