Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.54 |
| ▸ | MEN1 | O00255 | 9/20 | 0.54 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4960442 | 0.81 | MAPT (0.55) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL11496108 | 0.79 | MAPT (0.51) | KMT2AMEN1MAPTSMN1; SMN2HPGD | |
| SCHEMBL1706183 | 0.78 | KMT2A (0.65) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL3189929 | 0.74 | KMT2A (0.69) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL15347692 | 0.74 | TDP1 (0.53) | POLBALDH1A1MAPK1 | |
| SCHEMBL15347688 | 0.74 | TDP1 (0.53) | POLBALDH1A1MAPK1 | |
| SCHEMBL14871553 | 0.74 | KMT2A (0.59) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL13093155 | 0.73 | KMT2A (0.80) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL152811 | 0.73 | KMT2A (0.74) | POLBKMT2AMEN1MAPTLMNA | |
| SCHEMBL5817153 | 0.73 | KMT2A (0.74) | POLBKMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188489-A | Process for the production of 3-substituted amino-5-pyrazolones | FUJI PHOTO FILM CO., LTD. (JP) | 1980-02-12 | — | — | US | disclosed |