Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | CTSG | P08311 | 3/20 | 0.40 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.40 |
| ▸ | CMA1 | P23946 | 3/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040893 | 0.85 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ANPC1NAMPTGAA | |
| SCHEMBL18651717 | 0.81 | NAMPT (0.60) | SMN1; SMN2RAB9ANPC1NAMPTGAA | |
| SCHEMBL25970067 | 0.74 | RAB9A (0.59) | SMN1; SMN2RAB9ANPC1GAAHPGD | |
| SCHEMBL7121699 | 0.74 | RAB9A (0.59) | SMN1; SMN2RAB9ANPC1GAAHPGD | |
| SCHEMBL799425 | 0.72 | NAMPT (0.58) | SMN1; SMN2RAB9ANPC1NAMPTGAA | |
| SCHEMBL19349021 | 0.72 | NAMPT (0.58) | SMN1; SMN2RAB9ANPC1NAMPTGAA | |
| SCHEMBL29280657 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1GAAHPGD | |
| SCHEMBL27366046 | 0.71 | RAB9A (0.56) | SMN1; SMN2RAB9ANPC1GAAHPGD | |
| SCHEMBL10872706 | 0.71 | RAB9A (0.56) | SMN1; SMN2RAB9ANPC1GAAHPGD | |
| SCHEMBL8591354 | 0.71 | HPGD (0.49) | SMN1; SMN2RAB9ANPC1NAMPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4188489-A | Process for the production of 3-substituted amino-5-pyrazolones | FUJI PHOTO FILM CO., LTD. (JP) | 1980-02-12 | — | — | US | disclosed |