Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683168 | 0.88 | CXCL8 (0.50) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7685429 | 0.87 | MAPK1 (0.49) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| Methane SCHEMBL7684820 | 0.86 | MAPK1 (0.48) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7677999 | 0.83 | PTGS2 (0.52) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7676979 | 0.83 | PTGS2 (0.50) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7678055 | 0.82 | PTGS2 (0.54) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL11486479 | 0.82 | KMT2A (0.45) | KMT2ANPSR1ALDH1A1HPGDKDM4E | |
| SCHEMBL11500022 | 0.74 | PTGS2 (0.69) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7680904 | 0.73 | PTGS2 (0.70) | CXCL8AKR1B1PTGS1PTGS2GLO1 | |
| SCHEMBL7682276 | 0.73 | PTGS2 (0.42) | CXCL8AKR1B1PTGS1PTGS2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4213905-A | Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid salts | MCNEILAB, INC. (US) | 1980-07-22 | — | — | US | disclosed |