SCHEMBL11488708

SCHEMBL11488708

[S]C1=NCCc2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 2/20 0.59
NOS2 P35228 1/20 0.59
KDM4E B2RXH2 2/20 0.46
ALDH1A1 P00352 2/20 0.46
MAOA P21397 2/20 0.43
CES1 P23141 1/20 0.41
CYP2A6 P11509 1/20 0.38
MAOB P27338 1/20 0.38
TSHR P16473 1/20 0.36
PDPK1 O15530 1/20 0.35
PARP1 P09874 1/20 0.35
PARP10 Q53GL7 1/20 0.35
PARP11 Q9NR21 1/20 0.35
CYP19A1 P11511 3/20 0.35
HPGD P15428 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP11B2 P19099 2/20 0.34
CYP11B1 P15538 1/20 0.34
POLB P06746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29385430 0.74 NOS3 (0.59) NOS3NOS2KDM4EALDH1A1MAOA
SCHEMBL31219707 0.74 NOS3 (0.59) NOS3NOS2KDM4EALDH1A1MAOA
SCHEMBL12352549 0.74 NOS3 (0.59) NOS3NOS2KDM4EALDH1A1MAOA
SCHEMBL12937466 0.74 NOS3 (0.59) NOS3NOS2KDM4EALDH1A1MAOA
SCHEMBL4997776 0.74 NOS3 (0.59) NOS3NOS2KDM4EALDH1A1MAOA
SCHEMBL7454314 0.74 NOS3 (1.00) NOS3NOS2KDM4EALDH1A1MAOA
SCHEMBL30310 0.74 NOS3 (0.59) NOS3NOS2KDM4EALDH1A1MAOA
SCHEMBL11267501 0.74 NOS3 (0.59) NOS3NOS2KDM4EALDH1A1MAOA
SCHEMBL13783121 0.74 NOS3 (0.64) NOS3NOS2KDM4EALDH1A1MAOA
SCHEMBL30789182 0.74 NOS3 (1.00) NOS3NOS2KDM4EALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0008145-A2 Use of phenyliminomethylpyridine derivatives as fungicides and plant growth regulants compositions containing such derivatives and phenyliminomethylpyridine derivatives and their preparation SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1980-02-20 EP disclosed