SCHEMBL11489003

SCHEMBL11489003

CCOc1ccc(C(=O)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.66
HPGD P15428 4/20 0.66
MAPT P10636 4/20 0.66
MAOB P27338 1/20 0.65
KMT2A Q03164 2/20 0.63
NPSR1 Q6W5P4 1/20 0.63
RAB9A P51151 4/20 0.58
NPC1 O15118 3/20 0.58
PARP10 Q53GL7 1/20 0.56
LMNA P02545 3/20 0.54
MAPK1 P28482 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
KDM4E B2RXH2 2/20 0.54
TSHR P16473 2/20 0.54
HSD17B10 Q99714 2/20 0.54
MCL1 Q07820 1/20 0.54
PLK1 P53350 1/20 0.53
ALOX15 P16050 1/20 0.53
RECQL P46063 1/20 0.53
MEN1 O00255 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18868773 0.90 RAB9A (0.64) ALDH1A1HPGDMAPTMAOBKMT2A
SCHEMBL845348 0.87 NPSR1 (0.79) ALDH1A1HPGDMAPTKMT2ANPSR1
SCHEMBL11491371 0.87 MAPT (0.70) ALDH1A1HPGDMAPTMAOBRAB9A
SCHEMBL60209 0.85 NQO1 (0.67) ALDH1A1MAPTMAOBLMNAMAPK1
SCHEMBL11485414 0.85 KMT2A (0.61) ALDH1A1HPGDMAPTMAOBKMT2A
SCHEMBL9247959 0.84 TSHR (0.60) ALDH1A1HPGDMAPTRAB9AKDM4E
SCHEMBL1309989 0.83 GAA (0.66) ALDH1A1HPGDMAPTMAOBKMT2A
Hydrochloric Acid SCHEMBL2855974 0.83 NQO1 (0.64) ALDH1A1MAPTMAOBLMNAMAPK1
SCHEMBL8924890 0.83 MEN1 (0.58) ALDH1A1MAPTMAOBKMT2ARAB9A
SCHEMBL8924977 0.83 MAOB (0.57) ALDH1A1MAPTMAOBKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4220356-A Recording materials containing chromenoindoles FUJI PHOTO FILM CO., LTD. (JP) 1980-09-02 US disclosed