SCHEMBL11489205

SCHEMBL11489205

O=C(CCC1CCNCC1)N1CCNCC1

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 13/20 0.60
ITGA2B P08514 13/20 0.60
GNAI3 P08754 1/20 0.57
GNAO1 P09471 1/20 0.57
GNAI1 P63096 1/20 0.57
TPSAB1 Q15661 1/20 0.54
TPSD1 Q9BZJ3 1/20 0.54
TPSG1 Q9NRR2 1/20 0.54
F2R P25116 9/20 0.53
TP53 P04637 1/20 0.51
HSD11B1 P28845 1/20 0.49
ALDH1A1 P00352 1/20 0.47
ATM Q13315 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14303380 0.91 ITGB3 (0.59) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL8278505 0.89 ITGB3 (0.61) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL23978381 0.86 GNAI3 (0.59) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL3459102 0.86 ITGB3 (0.55) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL4195892 0.86 ITGB3 (0.55) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL10252946 0.86 TP53 (0.58) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL26067161 0.85 ITGB3 (0.54) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL11496439 0.81 DDB1 (0.51) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL4195847 0.80 ITGB3 (0.49) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL24802116 0.79 MEN1 (0.51) ITGB3ITGA2BGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4182382-A Thermoplastic resin-coated metallic substrate and the method of producing the same through use of a polyamide adhesive layer COLORGUARD CORPORATION (US) 1980-01-08 US disclosed