Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PPIB | P23284 | 1/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | PPID | Q08752 | 1/20 | 0.45 |
| ▸ | PPIG | Q13427 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11490031 | 0.93 | MAPK1 (0.47) | MAPK1MAPTEPHX2ALDH1A1HPGD | |
| SCHEMBL11489717 | 0.92 | MAPK1 (0.46) | MAPK1MAPTEPHX2ALDH1A1HPGD | |
| SCHEMBL11491335 | 0.91 | MAPK1 (0.46) | MAPK1MAPTEPHX2ALDH1A1HPGD | |
| SCHEMBL11489721 | 0.82 | MAPK1 (0.46) | MAPK1MAPTALDH1A1HPGDPPIB | |
| SCHEMBL11489741 | 0.82 | ALDH1A1 (0.50) | MAPK1MAPTEPHX2ALDH1A1HPGD | |
| SCHEMBL11495394 | 0.81 | MEN1 (0.51) | ALDH1A1HPGDMEN1KMT2ARAB9A | |
| SCHEMBL11491381 | 0.81 | LMNA (0.46) | MAPK1EPHX2KMT2ALMNAGAA | |
| SCHEMBL11496733 | 0.81 | MAPT (0.54) | MAPK1MAPTALDH1A1HPGDMEN1 | |
| SCHEMBL11490138 | 0.80 | MAPK1 (0.46) | MAPK1MAPTEPHX2ALDH1A1MEN1 | |
| SCHEMBL11491354 | 0.80 | PPID (0.53) | MAPTEPHX2ALDH1A1PPIDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202832-A | ANTILIPEMIC AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1980-05-13 | — | — | US | disclosed |