Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170122 | 0.83 | F2 (0.61) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL2722831 | 0.79 | F2 (0.61) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL17189502 | 0.78 | F2 (0.59) | F2PRSS1PRSS2PRSS3GAA | |
| Methane SCHEMBL28216690 | 0.78 | F2 (0.59) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL8204252 | 0.78 | F2 (0.59) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL28454107 | 0.76 | F2 (0.58) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL6634591 | 0.74 | F2 (0.71) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL12748381 | 0.74 | ALDH1A1 (0.62) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL10926045 | 0.74 | ALDH1A1 (0.62) | F2PRSS1PRSS2PRSS3GAA | |
| SCHEMBL5279394 | 0.74 | ALDH1A1 (0.62) | F2PRSS1PRSS2PRSS3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008343-A1 | Cephalosporin derivatives, processes for their preparation and pharmaceutical compositions containing them | CIBA-GEIGY AG (CH) | 1980-03-05 | — | — | EP | disclosed |