SCHEMBL6634591

SCHEMBL6634591

CC(C)=NNS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 3/20 0.71
PRSS1 P07477 3/20 0.71
PRSS2 P07478 3/20 0.71
PRSS3 P35030 3/20 0.71
ALDH1A1 P00352 7/20 0.60
GAA P10253 2/20 0.60
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
MMP1 P03956 1/20 0.57
MMP2 P08253 1/20 0.57
MMP9 P14780 1/20 0.57
MMP8 P22894 1/20 0.57
MMP13 P45452 1/20 0.57
POLB P06746 2/20 0.54
SMN1; SMN2 Q16637 1/20 0.53
KDM4E B2RXH2 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14906214 0.85 F2 (0.77) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL26006200 0.84 ALDH1A1 (0.71) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL13005490 0.84 F2 (0.65) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL28374501 0.84 ALDH1A1 (0.71) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL6637235 0.82 LMNA (0.61) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL14157098 0.82 F2 (0.63) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL6638730 0.82 F2 (0.63) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL6638734 0.82 F2 (0.63) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL24234216 0.81 F2 (0.61) F2PRSS1PRSS2PRSS3ALDH1A1
SCHEMBL22116321 0.81 F2 (0.61) F2PRSS1PRSS2PRSS3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP claimed
WO-2026102082-A1 ALKYLPHENYL SUBSTITUTED COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-15 WO disclosed
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. (US) 2026-05-14 US disclosed
US-20170035761-A1 CYTOTOXIC COMPOUNDS WHICH ARE INHIBITORS OF THE POLYMERISATION OF TUBULIN CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2017-02-09 US disclosed
EP-0876888-B1 Process for producing water-absorbing resins NIPPON CATALYTIC CHEM IND (JP) 2012-12-12 EP disclosed
CN-1816548-B cyclopropyl substituted oxazolidinone antibiotics and derivatives thereof MERCK & CO INC 2011-01-12 CN disclosed
CN-1816548-A cyclopropyl substituted oxazolidinone antibiotics and derivatives thereof MERCK & CO INC (US) 2006-08-09 CN disclosed
CN-1649866-A 3-cyclyl-5-(nitrogen-containing 5-membered ring) methyl-oxazolidinone derivatives and their use as antibacterial agents ASTRAZENECA AB (SE) 2005-08-03 CN disclosed
EP-1420044-A2 Rubber composition and pneumatic tire Bridgestone Corporation (JP) 2004-05-19 EP disclosed
US-6380288-B1 LOW HEAT GENERATION PROPERTY, AGING REISTANCE, ALSO FOR PRODUCING VIBRATION ISOLATORS, BELTS AND HOSES AS WELL AS TIRE MATERIALS SUCH AS TIRE TREADS, UNDERTREADS, CARCASSES, SIDE WALLS AND BEADS BRIDGESTONE CORPORATION 2002-04-30 US disclosed
US-6100305-A INCREASING ABSORPTION BY CRUSHING AND DRYING A CROSSLINKED HYDROGEL POLYMER; USING IN DIAPERS, SANITARY NAPKINS, WOUND HEALING MATERIAL; BUILDING MATERIAL AND SOIL, WATERPROOFING MATERIAL, PACKING MATERIAL NIPPON SHOKUBAI CO., LTD. (JP) 2000-08-08 US disclosed
EP-0909788-A1 RUBBER COMPOSITION AND PNEUMATIC TIRES Bridgestone Corporation (JP) 1999-04-21 EP disclosed
EP-0876888-A1 METHOD OF PRODUCTION OF WATER-ABSORBING RESIN Nippon Shokubai Co., Ltd. (JP) 1998-11-11 EP disclosed
US-4126737-A Anaeorbically hardening adhesives and sealants based on (meth)acrylic esters containing reaction products of glycidyl-(meth)acrylate and half esters containing carbonate groups HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1978-11-21 US disclosed
US-4107386-A Anaerobically hardening adhesives and sealants based on (meth)acrylic esters containing polycarbonates terminated by (meth)acrylic ester groups HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1978-08-15 US disclosed
US-4096323-A Anaerobically hardening adhesives and sealants based on (meth)acrylic esters containing reaction products of glycidyl(meth)acrylate and half esters of dicarboxylic acids HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DT) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170035761-A1 CYTOTOXIC COMPOUNDS WHICH ARE INHIBITORS OF THE POLYMERISATION OF TUBULIN TUBB1, TUBB, TUBB3 F2 4741/4885PRSS1 3042/4885PRSS2 3057/4885
US-20260132119-A1 Alkylphenyl Substituted Compounds, Compositions and Methods of Use GIPR, MC2R, GRPR F2 3506/4885PRSS1 3371/4885PRSS2 2865/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.