Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8185974 | 0.93 | HTR6 (0.43) | CHRNB2CHRNA3CHRNA4CHRNB4HTR6 | |
| Hydrochloric Acid SCHEMBL8186266 | 0.91 | HTR6 (0.42) | CHRNB2CHRNA3CHRNA4CHRNB4HTR6 | |
| SCHEMBL3153126 | 0.81 | CHRM5 (0.36) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL3153297 | 0.80 | CHRM5 (0.39) | CHRNB2CHRNA3CHRNA4CHRNB3CHRNA6 | |
| SCHEMBL3521419 | 0.76 | CHRNB2 (0.36) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNB3 | |
| SCHEMBL745860 | 0.76 | DPP4 (0.40) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNB3 | |
| SCHEMBL2321580 | 0.76 | DPP4 (0.40) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNB3 | |
| SCHEMBL747476 | 0.76 | DPP4 (0.40) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNB3 | |
| SCHEMBL23182198 | 0.76 | CA1 (0.38) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNB3 | |
| Piperazine SCHEMBL28147717 | 0.76 | CHRNB2 (0.33) | CHRNB2CHRNA3CHRNA4CHRNB4CHRNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182382-A | Thermoplastic resin-coated metallic substrate and the method of producing the same through use of a polyamide adhesive layer | COLORGUARD CORPORATION (US) | 1980-01-08 | — | — | US | disclosed |