Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | HTR7 | P34969 | 1/20 | 0.55 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.53 |
| ▸ | BAD | Q92934 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13770482 | 0.94 | NPC1 (0.69) | RAB9ANPC1HTR7PTPN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL20491214 | 0.92 | NPC1 (0.67) | RAB9ANPC1HTR7PTPN1SMN1; SMN2 | |
| SCHEMBL16853371 | 0.83 | L3MBTL1 (0.52) | RAB9ANPC1HTR7SMN1; SMN2FFAR1 | |
| Hydrochloric Acid SCHEMBL8794334 | 0.82 | BCL2L1 (0.55) | RAB9ANPC1HTR7BCL2L1BAD | |
| SCHEMBL15607726 | 0.82 | NPC1 (0.77) | RAB9ANPC1HTR7PTPN1SMN1; SMN2 | |
| SCHEMBL26584242 | 0.81 | NPC1 (0.82) | RAB9ANPC1HTR7PTPN1SMN1; SMN2 | |
| SCHEMBL11489631 | 0.81 | RAB9A (0.62) | RAB9ANPC1HTR7BCL2L1BAD | |
| SCHEMBL7864069 | 0.81 | SMN1; SMN2 (0.72) | RAB9ANPC1HTR7BCL2L1BAD | |
| SCHEMBL633279 | 0.79 | NPC1 (0.72) | RAB9ANPC1HTR7PTPN1SMN1; SMN2 | |
| SCHEMBL13670559 | 0.78 | NPC1 (0.69) | RAB9ANPC1HTR7BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |