Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | GLA | P06280 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL558515 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2ANPC1 | |
| SCHEMBL16402570 | 0.74 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10KMT2ANPC1 | |
| SCHEMBL7698945 | 0.74 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10KMT2ANPC1 | |
| SCHEMBL253753 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2ANPC1 | |
| SCHEMBL10809600 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2ANPC1 | |
| SCHEMBL1450345 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2ANPC1 | |
| SCHEMBL1450341 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2ANPC1 | |
| SCHEMBL20363016 | 0.74 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2ANPC1 | |
| Bromide SCHEMBL1186616 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10KMT2ANPC1 | |
| SCHEMBL6219388 | 0.71 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4234578-A | ANTIBIOTICS | CIBA-GEIGY CORPORATION (US) | 1980-11-18 | — | — | US | disclosed |