Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | RET | P07949 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
| ▸ | FLT1 | P17948 | 1/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LTK | P29376 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1186616 | 0.98 | KDM4E (0.53) | KDM4EALDH1A1RETKDRALK | |
| SCHEMBL11490669 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL7698945 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL1450341 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL1450345 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL20363016 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL253753 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL16402570 | 0.73 | KDM4E (0.56) | KDM4EALDH1A1FLT3HSD17B10KMT2A | |
| SCHEMBL10809600 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10KMT2AHPGD | |
| SCHEMBL14759162 | 0.72 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217571-B | Method for preparing medicine building block 1,2, 4-triazolo [4,3-A ] pyridine-3-amine | 上海锐谱医药科技有限公司 | 2024-11-15 | — | — | CN | claimed |
| CN-116217571-A | Method for preparing medicine building block 1,2, 4-triazolo [4,3-A ] pyridine-3-amine | 上海锐谱医药科技有限公司 | 2023-06-06 | — | — | CN | claimed |
| US-20250122182-A1 | MYST Inhibitors | Isosterix, Inc. | 2025-04-17 | — | — | US | disclosed |
| US-20250051343-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. | 2025-02-13 | — | — | US | disclosed |
| EP-4499609-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2025-02-05 | — | — | EP | disclosed |
| CN-119301096-A | Inhibitors of MYST family lysine acetyltransferase | 伊索斯泰里克斯公司 | 2025-01-10 | — | — | CN | disclosed |
| US-12187732-B2 | Inhibitors of the myst family of lysine acetyl transferases | Isosterix, Inc. (US) | 2025-01-07 | — | — | US | disclosed |
| CN-116217571-B | Method for preparing medicine building block 1,2, 4-triazolo [4,3-A ] pyridine-3-amine | 上海锐谱医药科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-116217571-B | Method for preparing medicine building block 1,2, 4-triazolo [4,3-A ] pyridine-3-amine | 上海锐谱医药科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-116217571-B | Method for preparing medicine building block 1,2, 4-triazolo [4,3-A ] pyridine-3-amine | 上海锐谱医药科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| WO-2023192817-A9 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2024-10-03 | — | — | WO | disclosed |
| US-7863291-B2 | Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-01-04 | — | — | US | disclosed |
| US-20100099684-A1 | Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | BRISTOL-MYERS SQUIBB COMPANY | 2010-04-22 | — | — | US | disclosed |
| US-20100099684-A1 | Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | BRISTOL-MYERS SQUIBB COMPANY | 2010-04-22 | — | — | US | disclosed |
| CN-101685733-A | High-temperature thermal fuse device | THERM O DISC INC | 2010-03-31 | — | — | CN | disclosed |
| US-20090270405-A1 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY | 2009-10-29 | — | — | US | disclosed |
| US-20090270405-A1 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY | 2009-10-29 | — | — | US | disclosed |
| WO-2009131926-A1 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009131926-A1 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009097971-A1 | TRIAZOLIUM SALTS AS PAR1 INHIBITORS, PRODUCTION THEREOF, AND USE AS MEDICAMENTS | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099684-A1 | Quinuclidine Compounds as Alpha-7 Nicotinic Acetylcholine Receptor Ligands | CHRNA7, CHRNA5, CHRNA6 | KDM4E 3667/4885ALDH1A1 1082/4885RET 1448/4885 |
| US-20250051343-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | KAT6A, KAT6B, KAT2A | KDM4E 227/4885ALDH1A1 1618/4885RET 3973/4885 |
| US-12187732-B2 | Inhibitors of the myst family of lysine acetyl transferases | KAT6A, KAT6B, KAT2A | KDM4E 227/4885ALDH1A1 1618/4885RET 3973/4885 |
| US-20090270405-A1 | QUINUCLIDINE COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | CHRNA7, CHRNA5, CHRNA6 | KDM4E 3667/4885ALDH1A1 1082/4885RET 1448/4885 |
| US-20250122182-A1 | MYST Inhibitors | MNAT1, SUGT1, ACAT2 | KDM4E 844/4885ALDH1A1 3906/4885RET 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.