SCHEMBL253753

SCHEMBL253753

Sc1nnc2ccccn12

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.55
ALDH1A1 P00352 6/20 0.55
HSD17B10 Q99714 3/20 0.47
KMT2A Q03164 3/20 0.47
NPC1 O15118 5/20 0.46
HPGD P15428 3/20 0.46
GLA P06280 2/20 0.46
GAA P10253 2/20 0.46
CASP1 P29466 1/20 0.46
CASP7 P55210 1/20 0.46
SMN1; SMN2 Q16637 6/20 0.46
RAB9A P51151 9/20 0.40
TDP1 Q9NUW8 1/20 0.40
ADORA3 P0DMS8 1/20 0.39
LMNA P02545 3/20 0.39
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylethylamine SCHEMBL10577674 0.84 KDM4E (0.50) KDM4EALDH1A1HSD17B10KMT2ANPC1
SCHEMBL10577062 0.77 KDM4E (0.40) KDM4EALDH1A1RAB9ALMNA
SCHEMBL10571879 0.76 KDM4E (0.39) KDM4EALDH1A1HSD17B10KMT2ANPC1
Hydrochloric Acid SCHEMBL10571375 0.76 KDM4E (0.44) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL10574086 0.75 CHRNA7 (0.59) KDM4EKMT2AGAASMN1; SMN2MEN1
SCHEMBL11490669 0.74 KDM4E (0.57) KDM4EALDH1A1HSD17B10KMT2ANPC1
SCHEMBL7698945 0.73 KDM4E (0.56) KDM4EALDH1A1HSD17B10KMT2ANPC1
SCHEMBL1450345 0.73 KDM4E (0.55) KDM4EALDH1A1HSD17B10KMT2ANPC1
SCHEMBL558515 0.73 KDM4E (0.55) KDM4EALDH1A1HSD17B10KMT2ANPC1
SCHEMBL6223669 0.70 ALDH1A1 (0.47) KDM4EALDH1A1HSD17B10KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2703062-B1 METHOD FOR ABSORBING ACID COMPOUNDS CONTAINED IN A GASEOUS EFFLUENT BY MEANS OF AN AMINE-BASED AQUEOUS SOLUTION IFP ENERGIES NOW (FR) 2022-10-12 EP claimed
US-10137404-B2 Method of absorbing acid compounds contained in a gaseous effluent using an amine-based aqueous solution IFP Energies Nouvelles (FR) 2018-11-27 US claimed
US-9139512-B2 Absorbent solution containing a degradation inhibitor derived from a triazole or from a tetrazole and method of absorbing acid compounds contained in a gaseous effluent IFP Energies Nouvelles (FR) 2015-09-22 US claimed
US-20140060328-A1 METHOD OF ABSORBING ACID COMPOUNDS CONTAINED IN A GASEOUS EFFLUENT USING AN AMINE-BASED AQUEOUS SOLUTION IFP Energies Nouvelles (FR) 2014-03-06 US claimed
EP-2703062-A2 Method for absorbing acid compounds contained in a gaseous effluent by means of an amine-based aqueous solution IFP Energies nouvelles (FR) 2014-03-05 EP claimed
EP-2459518-B1 ABSORBENT SOLUTION CONTAINING A DEGRADATION INHIBITOR DERIVED FROM A TRIAZOLE OR FROM A TETRAZOLE AND PROCESS FOR THE ABSORPTION OF ACID COMPOUNDS CONTAINED IN A GASEOUS EFFLUENT IFP Energies Nouvelles (FR) 2013-12-11 EP claimed
US-20120148463-A1 ABSORBENT SOLUTION CONTAINING A DEGRADATION INHIBITOR DERIVED FROM A TRIAZOLE OR FROM A TETRAZOLE AND METHOD OF ABSORBING ACID COMPOUNDS CONTAINED IN A GASEOUS EFFLUENT IFP Energies Nouvelles (FR) 2012-06-14 US claimed
EP-0254623-B1 AMINOALKYLTHIO TRIAZOLOPYRIDINE OR TRIAZOLOQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, PARTICULARLY USEFUL AS ANTALGICS LABORATOIRES UPSA (FR) 1993-06-09 EP claimed
WO-2024028169-A1 NOVEL SPECIFICALLY SUBSTITUTED THIOPHENOLIC COMPOUNDS NERVIANO MEDICAL SCIENCES S.R.L. (IT) 2024-02-08 WO disclosed
EP-2703062-B1 METHOD FOR ABSORBING ACID COMPOUNDS CONTAINED IN A GASEOUS EFFLUENT BY MEANS OF AN AMINE-BASED AQUEOUS SOLUTION IFP ENERGIES NOW (FR) 2022-10-12 EP disclosed
US-10137404-B2 Method of absorbing acid compounds contained in a gaseous effluent using an amine-based aqueous solution IFP Energies Nouvelles (FR) 2018-11-27 US disclosed
US-9139512-B2 Absorbent solution containing a degradation inhibitor derived from a triazole or from a tetrazole and method of absorbing acid compounds contained in a gaseous effluent IFP Energies Nouvelles (FR) 2015-09-22 US disclosed
US-20140060328-A1 METHOD OF ABSORBING ACID COMPOUNDS CONTAINED IN A GASEOUS EFFLUENT USING AN AMINE-BASED AQUEOUS SOLUTION IFP Energies Nouvelles (FR) 2014-03-06 US disclosed
EP-2703062-A2 Method for absorbing acid compounds contained in a gaseous effluent by means of an amine-based aqueous solution IFP Energies nouvelles (FR) 2014-03-05 EP disclosed
US-4419516-A Antiviral imidazo- and triazolo-pyridines AMERICAN HOME PRODUCTS CORPORATION (US) 1983-12-06 US disclosed
US-4368198-A BACTERICIDES ESPECIALLY ANTI-PSEUDOMONAS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1983-01-11 US disclosed
US-4302454-A Cephalosporins SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-11-24 US disclosed
US-4278793-A ANTIBIOTICS, BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DE) 1981-07-14 US disclosed
US-4234578-A ANTIBIOTICS CIBA-GEIGY CORPORATION (US) 1980-11-18 US disclosed
US-4165373-A ANTIBIOTICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1979-08-21 US disclosed