Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11481474 | 0.93 | MEN1 (0.55) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11474394 | 0.90 | KCNH2 (0.58) | KMT2AMAPTSMN1; SMN2KCNH2MAPK1 | |
| SCHEMBL11486208 | 0.90 | MAPT (0.50) | MEN1KMT2AMAPTTP53ABCB1 | |
| SCHEMBL11482563 | 0.88 | MEN1 (0.53) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11482582 | 0.88 | MEN1 (0.58) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11486191 | 0.85 | ABCB1 (0.53) | SMN1; SMN2ABCB1KCNH2 | |
| SCHEMBL11475983 | 0.84 | MEN1 (0.47) | MEN1KMT2ASMN1; SMN2ABCB1KCNH2 | |
| SCHEMBL11490020 | 0.84 | ABCB1 (0.55) | ABCB1POLBKCNH2 | |
| Hydrochloric Acid SCHEMBL11095607 | 0.83 | MEN1 (0.53) | MEN1KMT2AMAPTTP53SMN1; SMN2 | |
| SCHEMBL11474264 | 0.81 | SCN1A (0.47) | MEN1KMT2AMAPTTP53ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210753-A | TREATMENT OF CARDIAC DISORDERS AND CHRONIC LUNG DISEASE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-07-01 | — | — | US | disclosed |