Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11486208 | 0.90 | MAPT (0.50) | SCN1ASCN5ASCN9AMAPTMEN1 | |
| SCHEMBL11476354 | 0.86 | TSHR (0.54) | SCN1ASCN5ASCN9AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11079822 | 0.85 | HTR7 (0.51) | SCN1ASCN5ASCN9AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11482853 | 0.85 | TSHR (0.53) | SCN1ASCN5ASCN9AMAPTMEN1 | |
| SCHEMBL11474584 | 0.84 | SCN1A (0.49) | SCN1ASCN5ASCN9AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL11079825 | 0.84 | SCN1A (0.50) | SCN1ASCN5ASCN9AMAPTMEN1 | |
| SCHEMBL11490809 | 0.81 | MEN1 (0.55) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11474394 | 0.81 | KCNH2 (0.58) | MAPTKMT2ALMNAHTR7MAPK1 | |
| SCHEMBL11482582 | 0.81 | MEN1 (0.58) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL11475439 | 0.79 | MAPT (0.56) | SCN1ASCN5ASCN9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210753-A | TREATMENT OF CARDIAC DISORDERS AND CHRONIC LUNG DISEASE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1980-07-01 | — | — | US | disclosed |