SCHEMBL1149320

SCHEMBL1149320

CC(C)(CO)COB(O)O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL4902386 0.97 NUDT1 (0.30) NUDT1
Guanidine SCHEMBL1317562 0.89 NUDT1 (0.30) NUDT1
SCHEMBL29448377 0.86
SCHEMBL728114 0.84 NUDT1 (0.47) NUDT1
SCHEMBL5852179 0.80
SCHEMBL8679205 0.79
SCHEMBL9512818 0.75
SCHEMBL9714167 0.72
SCHEMBL31019791 0.72
SCHEMBL1236843 0.72 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814393-B2 Substituted guanidine compounds UBE CORPORATION (JP) 2023-11-14 US disclosed
US-20220315599-A1 SUBSTITUTED GUANIDINE COMPOUNDS UBE CORP (JP) 2022-10-06 US disclosed
US-11396514-B2 Substituted guanidine compounds UBE CORPORATION 2022-07-26 US disclosed
EP-3564230-B1 SUBSTITUTED GUANIDINE COMPOUND UBE INDUSTRIES (JP) 2022-02-09 EP disclosed
US-10759781-B2 Substituted guanidine derivatives UBE INDUSTRIES, LTD. (JP) 2020-09-01 US disclosed
US-20190337962-A1 SUBSTITUTED GUANIDINE COMPOUNDS UBE INDUSTRIES, LTD. (JP) 2019-11-07 US disclosed
EP-3564230-A1 SUBSTITUTED GUANIDINE COMPOUND UBE Industries, Ltd. (JP) 2019-11-06 EP disclosed
US-20190152953-A1 SUBSTITUTED GUANIDINE DERIVATIVES UBE INDUSTRIES, LTD. (JP) 2019-05-23 US disclosed
EP-1837373-B1 RESIN COMPOSITION AND FILM MADE OF SAME KURARAY CO (JP) 2019-03-13 EP disclosed
EP-3333163-A1 SUBSTITUTED GUANIDINE DERIVATIVE UBE Industries, Ltd. (JP) 2018-06-13 EP disclosed
EP-1369438-A1 BLOCK COPOLYMER AND THERMOPLASTIC RESIN COMPOSITION Kuraray Co., Ltd., Kurashiki Plant (JP) 2003-12-10 EP disclosed
WO-2003002664-A1 FLAME-RESISTANT POLYESTER MOULDING MATERIALS WITH POLYOLEFIN ADDITIVES BAYER AKTIENGESELLSCHAFT (DE) 2003-01-09 WO disclosed
WO-2003002643-A1 FLAME-PROOFED POLYESTER MOULDING MATERIALS WITH ZNS BAYER AKTIENGESELLSCHAFT (DE) 2003-01-09 WO disclosed
US-20020176955-A1 Fuel container having excellent gasoline barrier properties EVAL COMPANY OF AMERICA 2002-11-28 US disclosed
US-20020172788-A1 Method of producing a shaped article having excellent barrier properties KURARAY CO., LTD. (JP) 2002-11-21 US disclosed
EP-1245381-A1 Fuel container having excellent gasoline barrier properties Kuraray Co., Ltd. (JP) 2002-10-02 EP disclosed
EP-1230207-A2 METATHESIS SYNTHESES OF PHEROMONES OR THEIR COMPONENTS Pederson, Richard L. (US) 2002-08-14 EP disclosed
US-20020022741-A1 Metathesis syntheses of pheromones or their components MATERIA, INC. 2002-02-21 US disclosed
EP-1166892-A2 A method of producing a shaped article having excellent barrier properties Kuraray Co., Ltd. (JP) 2002-01-02 EP disclosed
WO-2001036368-A2 METATHESIS SYNTHESES OF PHEROMONES OR THEIR COMPONENTS PEDERSON RICHARD L (US) 2001-05-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10759781-B2 Substituted guanidine derivatives GMPS, GUCY1A1, GUCY1A2 NUDT1 195/4885
US-20220315599-A1 SUBSTITUTED GUANIDINE COMPOUNDS GMPS, PDE3B, GUCY1A2 NUDT1 145/4885
US-11814393-B2 Substituted guanidine compounds GMPS, PDE3B, GUCY1A2 NUDT1 145/4885
US-20190152953-A1 SUBSTITUTED GUANIDINE DERIVATIVES GMPS, GUCY1A1, GUCY1A2 NUDT1 195/4885
US-11396514-B2 Substituted guanidine compounds GMPS, PDE3B, GUCY1A2 NUDT1 145/4885
US-20190337962-A1 SUBSTITUTED GUANIDINE COMPOUNDS GMPS, PDE3B, GUCY1A2 NUDT1 145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.