SCHEMBL11493542

SCHEMBL11493542

CCOC(=S)c1sc(-c2cccnc2)nc1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.61
CYP1A2 P05177 4/20 0.61
CYP2C19 P33261 3/20 0.61
LMNA P02545 2/20 0.61
CDC7 O00311 4/20 0.55
DBF4 Q9UBU7 4/20 0.55
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2D6 P10635 1/20 0.51
MAPT P10636 3/20 0.48
KDM4E B2RXH2 2/20 0.45
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
TP53 P04637 1/20 0.43
BRAF P15056 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2881465 0.85 CDC7 (0.72) CYP3A4CYP1A2CYP2C19LMNACDC7
Hydrochloric Acid SCHEMBL6201525 0.84 CDC7 (0.70) CYP3A4CYP1A2CYP2C19LMNACDC7
SCHEMBL27817480 0.79 CYP1A2 (0.71) CYP3A4CYP1A2CYP2C19LMNACDC7
SCHEMBL29783018 0.77 CYP3A4 (0.77) CYP3A4CYP1A2CYP2C19LMNACDC7
SCHEMBL10066961 0.77 CYP3A4 (0.68) CYP3A4CYP1A2CYP2C19LMNACDC7
SCHEMBL1574577 0.77 CYP3A4 (0.77) CYP3A4CYP1A2CYP2C19LMNACDC7
SCHEMBL595294 0.77 CYP1A2 (0.77) CYP3A4CYP1A2CYP2C19LMNACDC7
SCHEMBL12725967 0.76 CYP1A2 (0.65) CYP3A4CYP1A2CYP2C19LMNACDC7
SCHEMBL11384459 0.76 CYP1A2 (0.67) CYP3A4CYP1A2CYP2C19LMNACDC7
SCHEMBL11398081 0.76 CYP1A2 (0.77) CYP3A4CYP1A2CYP2C19LMNACDC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4260765-A APHIDICIDES UNIROYAL, INC. (US) 1981-04-07 US disclosed
US-4080457-A INSECTICIDES, PESTICIDES, MITICIDES UNIROYAL CHEMICAL COMPANY, INC. 1978-03-21 US disclosed