Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.52 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.48 |
| ▸ | TTR | P02766 | 8/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.45 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.45 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11769100 | 0.91 | LTB4R (0.56) | LTB4RLTB4R2TTRNPC1RAB9A | |
| SCHEMBL11487862 | 0.89 | LTB4R (0.52) | LTB4RLTB4R2TTRKDM4EMEN1 | |
| SCHEMBL11769263 | 0.89 | LTB4R (0.65) | LTB4RLTB4R2TTRNPC1RAB9A | |
| SCHEMBL11769018 | 0.89 | TTR (0.52) | LTB4RLTB4R2TTRNPC1RAB9A | |
| SCHEMBL11495186 | 0.88 | LTB4R (0.56) | LTB4RLTB4R2TTRKDM4EMEN1 | |
| SCHEMBL11486603 | 0.85 | AKR1B1 (0.50) | LTB4RLTB4R2TTRNPC1RAB9A | |
| SCHEMBL11485941 | 0.85 | LTB4R (0.48) | LTB4RLTB4R2TTRNPC1RAB9A | |
| SCHEMBL11770191 | 0.85 | TTR (0.52) | LTB4RLTB4R2TTRNPC1RAB9A | |
| SCHEMBL11486396 | 0.84 | LTB4R (0.50) | LTB4RLTB4R2TTRKDM4EMEN1 | |
| SCHEMBL11485522 | 0.83 | LTB4R (0.49) | LTB4RLTB4R2TTRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217361-A | Disubstituted xanthone-2-carboxylic acid antiallergy agents | SYNTEX (U.S.A.) INC. (US) | 1980-08-12 | — | — | US | disclosed |