Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PHGDH | O43175 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8901518 | 0.82 | UPP1 (0.61) | UPP1KDM4EATMKMT2AMEN1 | |
| SCHEMBL16398184 | 0.81 | KDM4E (0.61) | UPP1KDM4EATMALDH1A1GAA | |
| SCHEMBL11121714 | 0.75 | UPP1 (0.69) | UPP1KDM4EATMKMT2AMEN1 | |
| SCHEMBL11496948 | 0.75 | UPP1 (0.53) | UPP1KDM4EATMKMT2AMEN1 | |
| SCHEMBL1086023 | 0.75 | UPP1 (0.53) | UPP1KDM4EATMKMT2AMEN1 | |
| SCHEMBL6655303 | 0.74 | UPP1 (0.68) | UPP1KDM4EATMKMT2AMEN1 | |
| SCHEMBL6625526 | 0.73 | UPP1 (0.66) | UPP1KDM4EATMKMT2AMEN1 | |
| SCHEMBL11835926 | 0.71 | UPP1 (0.49) | UPP1KDM4EATMKMT2AMEN1 | |
| SCHEMBL11051571 | 0.71 | UPP1 (0.56) | UPP1KDM4EATMKMT2AMEN1 | |
| SCHEMBL16561918 | 0.71 | UPP1 (1.00) | UPP1KDM4EATMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018091446-A1 | PROCESS FOR DYEING AND FOAMING THERMOPLASTIC POLYURETHANE | HUNTSMAN INTERNATIONAL LLC (US) | 2018-05-24 | — | — | WO | disclosed |
| EP-1532196-B1 | METHOD OF PRODUCING COLOURED PLASTICS OR POLYMERIC COLOUR PARTICLES | BASF SE (DE) | 2011-06-29 | — | — | EP | disclosed |
| EP-0019851-A1 | 1:2 Chromium complex dyestuffs of the azomethine and/or azo series, their preparation and use in dyeing and printing polyamide or cellulose materials | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |