Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.68 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.48 |
| ▸ | QPCT | Q16769 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11492274 | 0.88 | CYP19A1 (0.63) | CYP19A1CYP17A1CYP11B1CYP11B2LMNA | |
| SCHEMBL11495720 | 0.87 | CYP19A1 (0.61) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11494320 | 0.86 | CYP19A1 (0.54) | CYP19A1CYP17A1CYP11B1CYP11B2QPCT | |
| SCHEMBL11492519 | 0.86 | HMOX1 (0.59) | CYP19A1CYP11B1CYP11B2LMNASMN1; SMN2 | |
| SCHEMBL11487555 | 0.86 | CYP19A1 (0.49) | CYP19A1CYP11B1CYP11B2LMNASMN1; SMN2 | |
| SCHEMBL11494372 | 0.83 | CYP19A1 (0.53) | CYP19A1CYP11B1CYP11B2QPCT | |
| SCHEMBL5758394 | 0.81 | CYP19A1 (0.53) | CYP19A1CYP17A1QPCTLMNASMN1; SMN2 | |
| SCHEMBL28164874 | 0.79 | CYP19A1 (0.50) | CYP19A1CYP11B1CYP11B2LMNASMN1; SMN2 | |
| SCHEMBL11496005 | 0.79 | CYP19A1 (0.51) | CYP19A1LMNASMN1; SMN2 | |
| SCHEMBL11633201 | 0.78 | CYP19A1 (0.73) | CYP19A1CYP11B1CYP11B2QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4239759-A | Morpholino containing compounds, compositions and use thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1980-12-16 | — | — | US | disclosed |
| US-4110447-A | Anti-inflammatory (halo-4-biphenylyl)-alkanolamines | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1978-08-29 | — | — | US | disclosed |