Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793444 | 0.88 | ALDH1A1 (0.44) | ALDH1A1KMT2ASLC2A1L3MBTL1NCEH1 | |
| SCHEMBL8210145 | 0.83 | KMT2A (0.47) | ALDH1A1KMT2AL3MBTL1NCEH1SMN1; SMN2 | |
| SCHEMBL10440127 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KMT2AL3MBTL1NCEH1SMN1; SMN2 | |
| SCHEMBL18049812 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KMT2AL3MBTL1NCEH1SMN1; SMN2 | |
| SCHEMBL18032834 | 0.80 | KMT2A (0.44) | ALDH1A1KMT2ASMN1; SMN2NPC1MAPT | |
| SCHEMBL6933940 | 0.78 | SMN1; SMN2 (0.47) | ALDH1A1SLC2A1NCEH1SMN1; SMN2NPC1 | |
| SCHEMBL29372061 | 0.77 | ELANE (0.50) | ALDH1A1KMT2ASMN1; SMN2NPC1MAPT | |
| SCHEMBL20398449 | 0.77 | ELANE (0.50) | ALDH1A1KMT2ASMN1; SMN2NPC1MAPT | |
| SCHEMBL3041845 | 0.76 | HPGD (0.53) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL5963023 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TDP1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0014455-A2 | Cyclopropane(thiol)carboxylic-acid esters, processes for their preparation, pesticides containing such compounds and the use of such compounds as pesticides | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-08-20 | — | — | EP | disclosed |