Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NCEH1 | Q6PIU2 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210145 | 0.83 | KMT2A (0.47) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL10440127 | 0.83 | ALDH1A1 (0.56) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL30060732 | 0.82 | NCEH1 (0.46) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL10793444 | 0.82 | ALDH1A1 (0.44) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL11495787 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL18032834 | 0.80 | KMT2A (0.44) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL29372061 | 0.77 | ELANE (0.50) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL20398449 | 0.77 | ELANE (0.50) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL29369064 | 0.74 | ELANE (0.39) | ALDH1A1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL448000 | 0.73 | ALDH1A1 (0.60) | ALDH1A1KMT2ARAB9AL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268375-B1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | TRANSITIONS OPTICAL INC (US) | 2022-06-15 | — | — | EP | disclosed |
| CN-107406459-B | Photochromic thienobenzopyran compounds | 光学转变公司 | 2021-06-08 | — | — | CN | disclosed |
| US-20180051037-A1 | Photochromic Thienochromene Compounds | TRANSITIONS OPTICAL, INC. | 2018-02-22 | — | — | US | disclosed |
| EP-3268375-A1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | Transitions Optical, Inc. (US) | 2018-01-17 | — | — | EP | disclosed |
| WO-2016144324-A1 | PHOTOCHROMIC THIENOCHROMENE COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2016-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180051037-A1 | Photochromic Thienochromene Compounds | CRY1, CRY2, TERT | ALDH1A1 59/4885KMT2A 1594/4885SMN1; SMN2 4610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.