Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.90 |
| ▸ | CHAT | P28329 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL994764 | 0.97 | HDAC8 (0.95) | HDAC8CHATALDH1A1RAB9AKDM4E | |
| SCHEMBL271363 | 0.95 | — | — | |
| Water SCHEMBL9141383 | 0.92 | HDAC8 (0.95) | HDAC8CHATALDH1A1RAB9AKDM4E | |
| Bromide SCHEMBL366167 | 0.92 | HDAC8 (0.95) | HDAC8CHATALDH1A1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL541687 | 0.92 | HDAC8 (0.95) | HDAC8CHATALDH1A1RAB9AKDM4E | |
| Styrene SCHEMBL2988659 | 0.86 | HDAC8 (0.82) | HDAC8CHATALDH1A1RAB9AKDM4E | |
| Sulfuric Acid SCHEMBL8013239 | 0.82 | HDAC8 (0.75) | HDAC8CHATALDH1A1RAB9AKDM4E | |
| Sulfuric Acid SCHEMBL8013242 | 0.82 | HDAC8 (0.75) | HDAC8CHATALDH1A1RAB9AKDM4E | |
| Bicarbonate SCHEMBL31648035 | 0.82 | HDAC8 (0.75) | HDAC8CHATALDH1A1RAB9AKDM4E | |
| Sulfuric Acid SCHEMBL8013244 | 0.81 | HDAC8 (0.72) | HDAC8CHATALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4182797-A | AS CATHODE WITH LITHIUM ANODE, LITHIUM IODIDE ELECTROLYTE; USED FOR PACRMAKERS | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1980-01-08 | — | — | US | disclosed |