Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.95 |
| ▸ | CHAT | P28329 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271363 | 0.97 | — | — | |
| Water SCHEMBL9141383 | 0.95 | HDAC8 (0.95) | HDAC8CHATALDH1A1ACHEKDM4E | |
| Iodide SCHEMBL994764 | 0.95 | HDAC8 (0.95) | HDAC8CHATALDH1A1ACHEKDM4E | |
| Bromide SCHEMBL366167 | 0.95 | HDAC8 (0.95) | HDAC8CHATALDH1A1ACHEKDM4E | |
| Iodide SCHEMBL11496800 | 0.92 | HDAC8 (0.90) | HDAC8CHATALDH1A1ACHEKDM4E | |
| Styrene SCHEMBL2988659 | 0.88 | HDAC8 (0.82) | HDAC8CHATALDH1A1ACHEKDM4E | |
| Sulfuric Acid SCHEMBL8013239 | 0.84 | HDAC8 (0.75) | HDAC8CHATALDH1A1ACHEKDM4E | |
| Bicarbonate SCHEMBL31648035 | 0.84 | HDAC8 (0.75) | HDAC8CHATALDH1A1ACHEKDM4E | |
| Sulfuric Acid SCHEMBL8013242 | 0.84 | HDAC8 (0.75) | HDAC8CHATALDH1A1ACHEKDM4E | |
| Sulfuric Acid SCHEMBL8013244 | 0.83 | HDAC8 (0.72) | HDAC8CHATALDH1A1ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 365 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150342856-A1 | Cationic Comb Copolymers, Preparation Thereof And Use Thereof In Cosmetic, Pharmaceutical And Dermatological Formulations | CLARIANT FINANCE (BVI) LIMITED (VG) | 2015-12-03 | — | — | US | claimed |
| EP-2944658-A1 | Cosmetic, pharmaceutical and dermatological products | Clariant Produkte (Deutschland) GmbH (DE) | 2015-11-18 | — | — | EP | claimed |
| EP-1354000-B1 | USE OF COMB COPOLYMERS BASED ON ACRYLOYLDIMETHYLTAURINE ACID IN COSMETIC, PHARMACEUTICAL AND DERMATOLOGICAL PRODUCTS | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2015-05-27 | — | — | EP | claimed |
| EP-1363956-B1 | COMB-SHAPED COPOLYMERS BASED ON ACRYLOYLDIMETHYL TAURINE ACID | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2015-03-11 | — | — | EP | claimed |
| EP-1339382-B1 | DECORATIVE COSMETIC AND DERMATOLOGICAL PRODUCTS | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2015-02-25 | — | — | EP | claimed |
| EP-1339792-B1 | SURFACTANT-CONTAINING COSMETIC, DERMATOLOGICAL AND PHARMACEUTICAL AGENTS | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2015-02-25 | — | — | EP | claimed |
| EP-2186836-B1 | Cosmetic, pharmaceutical and dermatological medium. | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2014-06-25 | — | — | EP | claimed |
| EP-2194096-B1 | Use of pectinate copolymers on the basis of acryloyldimethyl taurine acid in cosmetic, dermatological and pharmaceutical agents | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2014-06-11 | — | — | EP | claimed |
| EP-2186835-B1 | Tenside-free cosmetic, dermatological and pharmaceutical medium. | CLARIANT PRODUKTE DEUTSCHLAND (DE) | 2014-05-21 | — | — | EP | claimed |
| EP-2414408-B1 | CATIONIC COMB COPOLYMERS, PREPARATION THEREOF AND USE THEREOF IN COSMETIC, PHARMACEUTICAL AND DERMATOLOGICAL FORMULATIONS | CLARIANT FINANCE BVI LTD (VG) | 2013-07-24 | — | — | EP | claimed |
| WO-2002043677-A2 | COSMETIC AND DERMATOLOGICAL HAIR-TREATMENT AGENTS | CLARIANT GMBH (DE) | 2002-06-06 | — | — | WO | claimed |
| WO-2002043686-A2 | ACID COSMETIC, DERMATOLOGICAL AND PHARMACEUTICAL AGENTS | CLARIANT GMBH (DE) | 2002-06-06 | — | — | WO | claimed |
| WO-2002044231-A1 | SURFACTANT-FREE COSMETIC, DERMATOLOGICAL AND PHARMACEUTICAL AGENTS | CLARIANT GMBH (DE) | 2002-06-06 | — | — | WO | claimed |
| WO-2002043687-A2 | DEODORANTS AND ANTI-PERSPIRANTS | CLARIANT GMBH (DE) | 2002-06-06 | — | — | WO | claimed |
| WO-2002044229-A1 | CATIONICALLY MODIFIED COMB POLYMERS BASED ON ACRYLOYLDIMETHYL TAURINE ACID | CLARIANT GMBH (DE) | 2002-06-06 | — | — | WO | claimed |
| WO-2002044224-A2 | COMB-SHAPED COPOLYMERS BASED ON ACRYLOYLDIMETHYL TAURINE ACID (2-ACRYLAMIDO-2-METHYL-1-PROPIONIC SULFONIC ACID | CLARIANT GMBH (DE) | 2002-06-06 | — | — | WO | claimed |
| WO-2002043688-A2 | DECORATIVE COSMETIC AND DERMATOLOGICAL PRODUCTS | CLARIANT GMBH (DE) | 2002-06-06 | — | — | WO | claimed |
| WO-2002044267-A2 | COSMETIC, PHARMACEUTICAL AND DERMATOLOGICAL PRODUCTS CONTAINING AN ELECTROLYTE | CLARIANT GMBH (DE) | 2002-06-06 | — | — | WO | claimed |
| WO-2002043689-A2 | COSMETIC, PHARMACEUTICAL AND DERMATOLOGICAL PRODUCTS | CLARIANT GMBH (DE) | 2002-06-06 | — | — | WO | claimed |
| EP-0145463-A2 | Dielectric sheet material | BENSON ELECTRONICS LIMITED (GB) | 1985-06-19 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150342856-A1 | Cationic Comb Copolymers, Preparation Thereof And Use Thereof In Cosmetic, Pharmaceutical And Dermatological Formulations | C9, PARN, SGMS1 | ACHE 3939/4885HDAC8 3471/4885CHAT 2035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.